Dr. Imran Ali will be participating at the World Conference on Analytical and Bioanalytical Chemistry held by Scientific Federation Prof. Imran Ali PhD, FRSC, C Chem, London (UK) is a world recognized academician and researcher. He completed his Ph.D. from Indian Institute of Technology Roorkee, Roorkee, India. Prof. Ali is known globally due his great contribution in separation science, chiral drugs development and water treatment. He has published more than 380 papers in reputed journals including papers in Nature and Chemical Reviews of more than 41 impact factors. He has also written five books published by Marcel Dekker, Inc., USA; Taylor & Francis, USA; John Wiley & Sons, USA; John Wiley & Sons, UK; Elsevier, The Netherlands. His citation is 13,500 with H index 48 and i10-index 174. Dr. Imran Ali is going to talk on

‘Nano chromatography and nano capillary electrophoresis: Need of this century.’ A brief summary is presented here.

In spite of the curing properties of the drugs, these remain in our body tissues at very low concentrations for long time; leading to serious side effects. Similarly, some environmental pollutants exist at very low concentration in the earth’s ecosystem. The normal analytical instruments are not capable to detect them. Hence, we consider these species as absent, which is an illusion to the scientists and the society. The concentrations of some hormones, RNAs, DNAs, antibodies and other proteins are very low. Availability of infant plasma and cerebrospinal fluids is very poor. The proteomics and genomics researches are extremely difficult and need miniaturization of the separation techniques. Besides, the increasing economic pressure of the costly chemicals is a big issue globally nowadays. In view of these facts, there is big demand of microscale separations with low detection limits. Due these facts the micro-total-analysis system (µ-TAS) has been developed and is being used in few laboratories of the world. These are nano liquid chromatography (NLC) and nano capillary electrophopresis (NCE) techniques. The proposed lecture will highlight the importance of these techniques with special emphasis onthe fabrication of microchip, instrumentation of NLC and NCE, detection,sample preparation, analyses and future perspectives.
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Dr. Heinz Siesler will be participating at the World Conference on Analytical and Bioanalytical Chemistry held by Scientific Federation. Dr. Heinz Siesler is a Professor of Physical Chemistry at the University of Duisburg-Essen, Germany, since 1987. His main research interests focus on the application of vibrational spectroscopy to chemical and polymer research and quality control. He has written 236 publications (including four monographs) and presented more than 275 lectures worldwide. He received the 1994 EAS Award, the 2000 Tomas Hirschfeld Award and the 2003 Buechi Award in near-infrared spectroscopy and he is a Fellow of the Society for Applied Spectroscopy (USA).He held guest professorships in France (1992), Japan (2000-2010) and Austria (2008-2017) and prior to his present academic position he gained extensive industrial experience from 1974-1987 in the Corporate R&D Department of Bayer AG, Germany. He also worked as lecturer at the University of the Witwatersrand, Johannesburg, South Africa (1972-1974) and as post-doc at the University of Cologne (1970-1972), Germany, after receiving his PhD in Chemistry from the University of Vienna, Austria, in 1970. Dr. Heinz Siesler is going to talk on ‘Handheld Vibrational Spectrometers: State-of-the-Art Instruments and their Realistic Applications.’ A brief summary is presented here.

Over the last decades vibrational spectroscopy (Raman, near-infrared, mid-infrared) is characterized by a multiplicity of hard- and software developments such ashyperspectral imaging, coupling with light-fiber optics and chemometric evaluation routines, but the application of these techniques so far remained a domain for scientists. In contrast, the recent developments of miniaturized, handheld spectrometers show promise for useful every-day-life applications by non-expert user environments. Inside the molecular spectrometer market, the fastest growing segment is miniature spectrometers and this market is expected to reach $ 300m by 2021.This significant growth will not only be based on a wider adoption of spectrometers for industrial process control and in-the-field/on-site testing but also on every-day-life consumer applications like food testing. The presentation will provide an overview on the building principles of the most recently introduced handheld vibrational spectrometers and critically highlight their performance and potential by means of selected application examples.

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Dr. Vakhtang Barbakadze will be participating at the World Conference on Analytical and Bioanalytical Chemistry held by Scientific Federation. Dr. Vakhtang Barbakadze has completed his Ph.D. and D.Sci. in 1978 and 1999 from Institute of Organic Chemistry, Moscow, Russia and Institute of Biochemistry and Biotechnology, Tbilisi, Georgia, respectively. He is the head of department of plant biopolymers and chemical modification of natural compounds at the Tbilisi State Medical University I.Kutateladze Institute of Pharmacochemistry. 1996 and 2002 he has been a visiting scientist at Utrecht University (faculty of pharmacy), The Netherlands, by University Scholarship and The Netherlands organization for scientific research (NWO) Scholarship Scientific Program, respectively. He has published more than 92 papers in reputed journals. Dr. Vakhtang Barbakadze is going to talk on ‘Structure characterization of plant macromolecule – prospective therapeutic agent’ A brief summary is presented here.

The 13C NMR experiment of water-soluble high-molecular preparations from different species of Boraginaceae family was carried out and simulated 13C NMR spectrum was calculated for 2-hydroxy-3-(3',4'-dihydroxyphenyl)-propionic acid residue (I) of the corresponding polyether using ACD/CNMR Version 1.1 program. Signal positions in the 13C NMR spectrum of this hypothetical structure (I) coincided satisfactory with the experimental values. According to 13C, 1H NMR, APT, 2D heteronuclear 1H/13C HSQC and 2D DOSY experiments the main structural element of these preparations was found to be a regularly substituted by 3,4-dihydroxyphenyl and carboxyl groups polyoxyethylene backbone, namely poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene] or poly[3-(3,4-dihydroxyphenyl)glyceric acid] (PDPGA). The synthesis of racemic monomer of PDPGA 2,3-dihydroxy-3-(3,4-dihydroxyphenyl)propionic acid (DDPPA) and its enantiomers (+)-(2R,3S)-DDPPA and (–)-(2S,3R)-DDPPA was carried out via Sharpless asymmetric dihydroxylation of trans-caffeic acid derivatives using a potassium osmate catalyst and enantiocomplementary catalysts cinchona alkaloid derivatives (DHQ)2-PHAL and (DHQD)2-PHAL as chiral auxiliaries. The opposite configuration of both enantiomers was confirmed by measurements of the optical rotation (+)/(–)-values and circular dichroism spectra. The determination of enantiomeric purity was performed by HPLC analysis. PDPGA and DDPPA exerted anti-cancer efficacy in vitro and in vivo against human prostate cancer (PCA) cells via targeting androgen receptor, cell cycle arrest and apoptosis without any toxicity, together with a strong decrease in prostate specific antigen level in plasma. However, our results showed that anticancer efficacy of PDPGA is more effective compared to its synthetic monomer. Overall, this study identifies PDPGA as a potent agent against PCA without any toxicity, and supports its clinical application.
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Dr. Ramanujachary will be participating at the World Conference on Analytical and Bioanalytical Chemistry held by Scientific Federation. Dr. Ramanujachary has completed his PhD from Indian Institute of Technology, and postdoctoral studies from Rutgers University, NJ, University, USA. He is currently working as a professor at the Department of Chemistry and Biochemistry at Rowan University. He has published more than 220 papers in reputed journals and holds several patents. Dr. Ramanujachary is going to talk on ‘Analytical Methods for the Conversion of Wasted Biomass to Value Added Chemicals’ A brief summary is presented here.

Rapid depletion of non-renewable fossil resources is posing an imminent threat to the energy and supply of fine chemicals that are vital to the global economy. Conversion of Biomass to value added chemicals has been on the forefront of strategies that are focused on eliminating our dependence on non-renewable resources such as coal and petroleum. Studies in the last two decades have resulted in the efficient conversion of corn to ethanol, at the same time escalating the corn prices beyond the reach of poor. In our research we have shifted our focus to the utilization of wasted biomass which does not interfere with the human or animal food chain. Use of sugar cane bagasse, switch grass, corn stover and wood from natural forests has been contemplated for bio-mass conversion to renewable fuels/chemicals. In this context, there exists a dire need to develop novel analytical separation methods and cost-effective materials to increase the efficiency of the conversion processes. For the conversion we have designed and developed novel catalytic materials with the efficiencies superior to those that currently exist. They have conducted the research in several phases in which the biomass is pretreated and the cellulose component has been separated from the lignin using mild and non-corrosive acids. The cellulose is subsequently converted to sugars which are broken down to glucose and fructose. Dehydration of sugars to hydroxymethyl furfural (HMF) is achieved by a novel catalyst featuring both Lewis and Bronstead acid sites. The presentation will summarize the importance of analytical techniques in the determination/separation of various products and opportunities for exploring inorganic materials for the production of value added chemicals and fuels.
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The London Metropolitan Police Service is kitting out its team of cyber security experts with a new set of real-time forensic analysis tools. On Thursday, the Met confirmed it teamed up with cyber security company Bromium to transform the way it investigates and responds to cyber crime. Based in California, Bromium is providing the Met with its latest micro-virtualization technology, which allows experts to analyse malware quickly and securely.

Bromium's forensic tools are designed to catch crooks specializing in malware attacks. Bromium claims the tools can quickly identify how attacks manifest, letting the force respond effectively. As part of the partnership, members of the public will be able to get in touch with the unit if they suspect malware attacks. The cyber specialists will then be able to respond as appropriate. The unit said it'll share intelligence with authorities such as Europol and NCSC to use as evidence when attempting to take down cyber criminals.