Bioanalytical Methods

Dr. Shyamal Kumar Chattopadhyay will be participating at the World Conference on Analytical and Bioanalytical Chemistry held by Scientific Federation. Dr. Shyamal Kumar Chattopadhyay has completed his PhD from Indian Association for the Cultivation of Science, Jadavpur, India in 1988 and was a Brain-Pool vesting scientist at KRICT, South Korea during 2006-2007. He is a faculty at IIEST, Shibpur since 1989 and is Professor since July 2006. He has published more than 80 papers in reputed journals. Dr. Shyamal Kumar Chattopadhyay is going to talk on ‘Chemodosimetric detection of HOCl/OCl− using a Ni(II) complex as a ratiometric fluorescent probe and its real applications.’ A brief summary is presented here.

Vitamin B6 cofactor derived ligand H2Bala-pydx was synthesized by condensation of pyridoxal hydrochloride with beta-alanine. Its complex with Ni(II) isolated and characterized using analytical and spectroscopic techniques. X-ray crystal structure confirmed the formulation of the compound as [Ni(HBala-pydx)2]·2H2O·CH3OH (NHBP) . The Ni(II) complex NHBP can be used as a fluorescent chemodosimeter and it serves as a highly sensitive and selective fluorescent sensor for the detection of HOCl/OCl− at pH 7.4. The reaction based approach towards the metal complex makes the fluorescent probe highly effective for detection of OCl− in tap water and living cells. It is also shown a simple low cost dip-stick can be designed using this complex for qualitative/ semi-quantitative detection of HOCl/OCl−. The detection is highly specific in presence of other ROS.
For more information : http://www.scientificfederation.com/analytical-chemistry-2018/